1. Vitamin D may fight disease
by Admin
Posted on 12-03-2024 11:50 AM
Vitamin d helps regulate the renin-angiotensin-aldosterone system (and thereby blood pressure), vascular cell growth, and inflammatory and fibrotic pathways [ 118 ]. Vitamin d deficiency is associated with vascular dysfunction, arterial stiffening, left ventricular hypertrophy, and hyperlipidemia [ 119 ]. For these reasons, vitamin d has been linked to heart health and risk of cvd. Observational studies support an association between higher serum 25(oh)d levels and a lower risk of cvd incidence and mortality.
For example, a meta-analysis included 34 observational studies that followed 180,667 participants (mean age greater than 50 years) for 1. 3 to more than 32 years.
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The most serious complications of vitamin d deficiency include: low blood calcium levels (hypocalcemia). Low blood phosphate levels (hypophosphatemia). Rickets (softening of bones during childhood). Osteomalacia (softening of bones in adults). All of these conditions are treatable. While rickets is a treatable and often curable disease, treating it as soon as possible is important. When not treated, milder cases of rickets can result in long-term bone damage that can keep bones from growing properly. Severe cases that aren’t treated can lead to seizures, heart damage and death. The good news is that thanks to vitamin d-fortified infant formula and fortified cow’s milk, rickets is very uncommon in the united states.
Vitamin d is stored mainly in the liver. Vitamin d2 and d3 are not active in the body. Both forms must be processed (metabolized) by the liver and kidneys into an active form called active vitamin d or calcitriol. This active form promotes absorption of calcium and phosphorus from the intestine. Calcium and phosphorus, which are minerals, are incorporated into bones to make them strong and dense (a process called mineralization). Thus, calcitriol is necessary for the formation, growth, and repair of bones. , hypoparathyroidism hypoparathyroidism hypoparathyroidism is a deficiency of parathyroid hormone (pth) often caused by an autoimmune disorder, treatment-related damage to the parathyroid glands, or removal of the glands during surgery.
2. Vitamin D may regulate mood and reduce depression
Here are some of the benefits associated with vitamin d :
contributes to bone health by aiding in calcium absorption into the bones, as well as other vitamins and minerals that contribute to skeletal health , including magnesium, vitamin k and phosphorus. Supports the immune system and may help prevent prolonged or excessive inflammatory responses, plus some viruses and infections.
Can help support healthy cell replication and may play a role in protecting against the development of autoimmune conditions. Promotes cardiovascular health and helps regulate blood pressure, cholesterol levels and inflammation. Helps manage blood sugar levels and works with calcium to regulate insulin secretion.
Observational studies indicate that greater body weights are associated with lower vitamin d status, and individuals with obesity frequently have marginal or deficient circulating 25(oh)d levels [ 151 ]. However, clinical trials do not support a cause-and-effect relationship between vitamin d and weight loss. A systematic review and meta-analysis of 15 weight-loss intervention studies that used caloric restriction, exercise, or both, but not necessarily vitamin d supplementation or other treatments, found that people who lost weight had significantly greater increases in serum 25(oh)d levels than those who maintained their weight [ 152 ]. In another study, 10 mcg (400 iu)/day vitamin d and 1,000 mg/day calcium supplementation slightly, but significantly, reduced weight gain amounts in comparison with placebo in postmenopausal women, especially those with a baseline total calcium intake of less than 1,200 mg/day [ 153 ].