Vitamin B6 and Health
by Admin
Posted on 23-04-2024 01:13 PM
Recommendations for vitamin b6, as well as other nutrients, are provided in the dietary reference intakes (dris) developed by the food and nutrition board at the national academies of sciences, engineering, and medicine. Dri is a term for a set of reference intakes that are used to plan and assess the nutrient intakes of healthy people. These values, which vary by age and sex, include:
recommended dietary allowance (rda): the average daily level of intake that is enough to meet the nutrient needs of nearly all (97% to 98%) healthy people.
An rda is an intake level based on scientific research evidence.
Intake recommendations for vitamin b6 and other nutrients are provided in the dietary reference intakes (dris) developed by the fnb [ 1 ]. Dri is the general term for a set of reference values used for planning and assessing nutrient intakes of healthy people. These values, which vary by age and gender, include the following: recommended dietary allowance (rda): average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%–98%) healthy individuals; often used to plan nutritionally adequate diets for individuals adequate intake (ai): intake at this level is assumed to ensure nutritional adequacy; established when evidence is insufficient to develop an rda. https://www.specialistsupplements.com/product-category/cleanse-and-detox/
People who eat a balanced diet should meet the daily requirement for vitamin b6 without taking a supplement. As with all medications and supplements, check with a health care provider before giving vitamin b6 supplements to a child. Daily recommendations for dietary vitamin b6 are: pediatric infants, 0 to 6 months: 0. 1 mg (adequate intake) infants, 7 months to 1 year: 0. 3 mg (adequate intake) children, 1 to 3 years: 0. 5 mg (rda) children, 4 to 8 years: 0. 6 mg (rda) children, 9 to 13 years: 1 mg (rda) boys, 14 to 18 years: 1. 3 mg (rda) girls, 14 to 18 years: 1.
Amino acid metabolism [ edit ]
Vitamin b6 is one of the b vitamins , and thus an essential nutrient.
The term refers to a group of six chemically similar compounds, i. E. , " vitamers ", which can be interconverted in biological systems. Its active form, pyridoxal 5′-phosphate , serves as a coenzyme in more than 140 enzyme reactions in amino acid , glucose , and lipid metabolism. Plants synthesize pyridoxine as a means of protection from the uv-b radiation found in sunlight and for the role it plays in the synthesis of chlorophyll. Animals cannot synthesize any of the various forms of the vitamin, and hence must obtain it via diet, either of plants, or of other animals.
Vitamin b6 must be obtained from the diet because humans cannot synthesize it. Plp plays a vital role in the function of over 100 enzymes that catalyze essential chemical reactions in the human body (4). Plp-dependent enzymes have been classified into five structural classes known as fold type i-v (5) : fold type i - aspartate aminotransferase family fold type ii - tryptophan synthase family fold type iii - alanine racemase family fold type iv - d-amino acid aminotransferase family fold type v - glycogen phosphorylase family the many biochemical reactions catalyzed by plp-dependent enzymes are involved in essential biological processes, such as hemoglobin and amino acid biosynthesis, as well as fatty acid metabolism.
Vitamin b6 is a fascinating molecule involved in the vast majority of changes in the human body because it is a coenzyme involved in over 150 biochemical reactions. It is active in the metabolism of carbohydrates, lipids, amino acids, and nucleic acids, and participates in cellular signaling. It is an antioxidant and a compound with the ability to lower the advanced glycation end products (age) level. In this review, we briefly summarize its involvement in biochemical pathways and consider whether its deficiency may be associated with various diseases such as diabetes, heart disease, cancer, or the prognosis of covid-19.
European food safety authority. 2016. Scientific opinion on dietary reference values for vitamin b6. Efsa journal 2016;14(6):4485 world health organization (who). 2004. Vitamin and mineral requirements in human nutrition. 2nd edition. Geneva, switzerland: who. Public health england. 2019. Mccance and widdowson’s composition of foods integrated dataset.