Rhinophyma involves an increase in sebaceous, or oil, glands and underlying connective tissues in the face. According to , the exact cause is still unclear, and several factors may play a role. These include a combination of conditions that affect the immune system, nerves, and blood vessels. The precursor to rhinophyma is acne rosacea, a long-term skin condition that is more common in females. A subset of people with acne rosacea later develops rhinophyma. Rhinophyma occurs more often in males, at a ratio ranging from and it typically develops in people aged 50–70. Due to the higher prevalence in males, scientists suspect that male hormones increase the risk. The exact cause of rhinophyma is not well understood, but it is believed to be a complication of rosacea, a chronic skin condition that affects the face. Rosacea causes inflammation and redness on the face, especially on the cheeks, nose, chin, and forehead. In some people, the condition can progress to rhinophyma, which is characterized by the thickening of the skin on the nose and an increase in the number and size of sebaceous glands. There are some risk factors that have been associated with the development of rhinophyma, including:. IS RHINOPHYMA