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Signs of Addiction: You may have one or more of these warning signs: An urge to take the substance every day, or many times a day. Taking more drugs than you want to, and for longer than you thought you would. Always having the drug with you, and buying it even if you can’t afford it. Using drugs even if they cause you trouble at work or make you lash out at family and friends. Spending more time alone. Not taking care of yourself or caring how you look. Stealing, lying, or doing dangerous things, like driving while high or having unsafe sex. Spending most of your time procuring, using, or recuperating from the affects of the substance. Feeling nauseous when you attempt to quit.
The brain adapts to drug use by decreasing its ability to respond to reward circuit stimuli. This reduces the person’s high compared to when they first took the drug. This is known as tolerance. For the same effect, they might need to take more of the drug. People with brain changes often find it harder to enjoy once-loved activities, such as eating and sex.

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Who has the highest chance of addiction? Every person is unique in their body and brain. People also react differently to drugs. Some people feel the drug's effects immediately and then want more. Some people dislike it and stop trying.
Inability to quit is the hallmark sign of addiction. It is not a good idea to quit when your health is at risk. Not if you are causing financial, emotional, and other problems for your family members or loved ones. Even if it's your intention to quit using drugs altogether, you might find that the desire to acquire and use them is consuming every waking minute of your day.

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Your brain's reward system is where drugs can cause addiction. Dopamine, which is a neurotransmitter in your brain, is released in large quantities. This creates an incredible feeling of joy. The high is repeated until you get it again.
Which person is most likely to become addicted? Every person is unique. Different people react to medication differently. Some people love it the first time they attempt it, and others want more. Some people hate it and will never attempt it again.

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A person who cannot quit is the hallmark of addiction. You should not quit if it is a risk to your health. You should not use drugs if it causes financial, emotional, or other difficulties for you and your loved ones. Even if your goal is to quit using drugs completely, it's possible that you find that the desire to obtain and use them takes over every waking hour.
Your brain will eventually adapt to the increased levels dopamine. It is possible to need to take more medicine to achieve the same effect. Even things that used be so important to you, like family time and eating well, might no longer bring you joy.

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Who’s Most Likely to Become Addicted? Each person’s body and brain are different. People also react differently to medications. Some love the feeling the first time they try it and want more. Others despise it and never try again.
If you keep using medications, your brain will adapt by lowering the ability of cells in the reward circuit to respond to it. While the person is still abusing drugs, this will continue to happen. When a person's tolerance for a substance wears off, the high they get from it isn't as intense as when they first started using it. They may be able to get the same effect by taking a larger amount of the chemical. As a result of these changes in brain function, the individual may discover that they are no longer able to enjoy activities such as eating or sexual engagement.

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You can potentially develop an addiction to prescription or illicitly acquired opioid painkillers. This issue has reached pandemic proportions in the United States. In 2018, opioids contributed to the majority of drug overdose deaths.
Your brain will adjust to the increased dopamine gradually. To get the same high, you may need to consume more of this substance. Other activities that you enjoyed, such as cooking and spending time with loved ones, may now be less enjoyable.